Probably, if the kind of business you are running is a very big business then keeping the money in the bank is actually the best thing to do. You should not keep a lot of money at home.Well, for small enterprises, I would suggest that you take the cash home and perhaps leave some there to be used the following day in case a customer needed a balance of cash after making a purchase.
However, if your business is substantial and well-established, you should never leave your money at home or in the office; instead, put it in the bank.