Taking a loan to start up a business depends the kind of business you really wants to start, but me I don't like taking a loan to start up a business I will like to save enough money before going into business.if you're starting a business, it's virtually impossible to get a loan from a bank or online lender in your company's first year. Lenders require cash flow to support repayment of the loan, so startups are typically disqualified from financing.